Pyrimidine nucleosides
Medchemexpress LLC Deoxycytidine 5'-triphosphate, trisodium salt | 109909-44-6 | 99.5% | 533.10 g/mol | C9H13N3Na3O13P3 | 25 MG
Deoxycytidine triphosphate (trisodium) is provided as a ready-to-use 100 mM aqueous solution of the trisodium salt of dCTP. It functions as a nucleotide substrate for DNA synthesis, polymerase reactions, and enzymatic assays, and is supplied as a high-purity solution intended for molecular biology workflows.
- High purity: 99.46% suitable for sensitive assays.
- Ready-to-use 100 mM aqueous solution for immediate use.
- Trisodium salt form enhances solubility in aqueous buffers.
- Colorless to light yellow liquid for easy visual inspection.
- Available in small pack sizes (for example, 25 mg) to reduce waste.
- Storage-stable when frozen; follow manufacturer storage guidance.
Medchemexpress LLC 2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) | 13085-50-2 | MFCD00069774 | 98.0% | 351.16 | 500 MG
2'-Deoxycytidine-5'-monophosphoric acid disodium (dCMP disodium) is an endogenous metabolite. This product is intended for research use only and is not for sale to patients.
- Endogenous metabolite
- For research use only
Cambridge Isotope Laboratories 5-Fluoro-2-deoxyuridine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
5-Fluoro-2-deoxyuridine 5-triphosphate ammonium salt (unlabeled) (in solution) CP 95% 100 umol
Medchemexpress LLC KTX-951 | 2573298-36-7 | 99.6% | 850.95 | 1 MG
KTX-951 is an orally active PROTAC degrader targeting IRAK4 and IMiD (Ikaros/Aiolos) substrates. It exhibits a Kd of 3.5 nM for IRAK4, with DC50 values of 13 nM, 14 nM, and 13 nM for IRAK4, Ikaros, and Aiolos, respectively. This compound also shows an IC50 of 35 nM for OCl-Ly10 CTG and demonstrates antitumor activity.
- Orally active PROTAC degrader
- Targets IRAK4 and IMiD (Ikaros/Aiolos) substrates
- Kd of 3.5 nM for IRAK4
- Molecular weight: 850.95
- Formula: C46H52F2N8O6
- Appearance: Solid, light yellow to yellow
- Purity: 99.60%
- Soluble in DMSO at 50 mg/mL (58.76 mM)
- Oral bioavailability in rats: 22% at 10 mg/kg
- Oral bioavailability in dogs: 57% at 10 mg/kg
Cayman Chemical 5-Bromo-2-deoxyurIdIn 1g
A thymidine nucleoside derivative commonly used to identify proliferating cells; intraperitoneal injection of BrdU can be used in combination with neuronal markers to detect adult neurogenesis in animal models; commonly used as a marker of proliferation of cancer cells in vitro
Research Products International Corp RPI 2'-Deoxycytidine Hydrochloride, 25 Grams
2'-Deoxycytidine Hydrochloride
Cambridge Isotope Laboratories 2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 100 UMOL
2'-DEOXYURIDINE:AMMONIUM SALT 90% CHEMICAL PURITY (13C9, 98-99%; 15N2, 98-99%) (IN SOLN), 100 UMOL
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | MFCD00006547 | 99.95% | 25 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and is utilized in cancer research.
- Inhibits biological effects of Bromodeoxyuridine (Brdu)
- Essential for nucleic acid synthesis
- Utilized in cancer research
- Acts as a human endogenous metabolite
- Functions as a microbial metabolite
- Demonstrated to inhibit tumor growth in vivo
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 100.0% | 10 MM 1 ML
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. It serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. Additionally, 2'-deoxyuridine reduces microglial activation and improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury, showing promise for Alzheimer's disease (AD) research.
- Brain-penetrant pyrimidines nucleotide associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Reduces microglial activation.
- Improves oxidative stress damage by modulating glycolytic metabolism on Aβ25-35-induced brain injury.
- Promising for Alzheimer's disease (AD) research.
![eMolecules 69304-47-8 | (E)-5-(2-Bromovinyl)-2'-deoxyuridine | Chem-Impex333.138 | C11H13BrN2O5 | 99.000 | OCC1OC(CC1O)n1cc(C=CBr)c(=O)[nH]c1=O | 1g | 272388689](https://assets.fishersci.com/TFS-Assets/CCG/product-images/501716765.jpg-250.jpg)
eMolecules 69304-47-8 | (E)-5-(2-Bromovinyl)-2'-deoxyuridine | Chem-Impex333.138 | C11H13BrN2O5 | 99.000 | OCC1OC(CC1O)n1cc(C=CBr)c(=O)[nH]c1=O | 1g | 272388689
(E)-5-(2-Bromovinyl)-2'-deoxyuridine | Chem-Impex | 69304-47-8333.138 | C11H13BrN2O5 | 99.000 | OCC1OC(CC1O)n1cc(C=CBr)c(=O)[nH]c1=O | 1g | 272388689
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 500 MG
2'-Deoxyuridine is a brain-penetrant pyrimidines nucleotide associated with nervous system diseases. It can increase chromosome breakage and decrease thymidylate synthetase activity. This product serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has shown promise in Alzheimer's disease (AD) research by reducing microglial activation and improving oxidative stress damage through modulation of glycolytic metabolism on Aβ25-35-induced brain injury.
- Associated with nervous system diseases.
- Increases chromosome breakage.
- Decreases thymidylate synthetase activity.
- Precursor in the synthesis of edoxudine.
- Analogue of 5-ethynyl-2'-deoxyuridine.
- Reduces microglial activation.
- Improves oxidative stress damage.
Medchemexpress LLC 2'-Deoxycytidine | 951-77-9 | 99.95% | 1 G
2'-Deoxycytidine is a deoxyribonucleoside that can inhibit the biological effects of Bromodeoxyuridine (Brdu). It is essential for the synthesis of nucleic acids and can be used for cancer research.
- Inhibits biological effects of Brdu.
- Essential for nucleic acid synthesis.
- Used in cancer research.
- Inhibits tumor growth in vivo.
Medchemexpress LLC 2'-Deoxycytidine (Standard) | 951-77-9 | MFCD00006547 | 99.95% | 50 MG
2'-Deoxycytidine (Standard) is an analytical standard used as a reference for assays. It is commonly employed in various research experiments, including qualitative, quantitative, and methodological studies.
- Serves as a reference standard for assays.
- Utilized in qualitative research experiments.
- Utilized in quantitative research experiments.
- Utilized in methodological research experiments.
- Applicable in HPLC (High-Performance Liquid Chromatography).
- Applicable in GC (Gas Chromatography).
- Applicable in MS (Mass Spectrometry).
Medchemexpress LLC 2'-Deoxyuridine | 951-78-0 | 99.98% | 1 G
2'-Deoxyuridine is a brain-penetrant pyrimidine nucleotide associated with nervous system diseases. It can increase chromosome breakage and reduce thymidylate synthetase activity. This compound serves as a precursor in the synthesis of Edoxudine and is an analogue of 5-ethynyl-2'-deoxyuridine. It has demonstrated the ability to lessen microglial activation and enhance oxidative stress damage by modulating glycolytic metabolism in brain injury models, indicating its potential for Alzheimer's disease research.
- Brain-penetrant pyrimidine nucleotide.
- Associated with nervous system diseases.
- Can increase chromosome breakage.
- Reduces thymidylate synthetase activity.
- Precursor in synthesis.
- Analogue of other compounds.
- Reduces microglial activation.
- Improves oxidative stress damage.
- Modulates glycolytic metabolism in brain injury.
- Promising for Alzheimer's disease research.